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Structural variations (large deletions, inversions i.e. copy number variations and duplications & translocations) contribute to genome variability and are often associated with diseases.

This technology can be used to generate monosomic and trisomic syndromes in the mouse.

 
 Target DNA
  > > >
 
Inversion
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Z flèche bas grosse
  >   >
Z flèche haut droit grosse  
Z flèche droite grosse
Duplication
> > > >
    >  
Z flèche bas droit grosse  
   
Deletion
> >    

 

Which technic can be used

PHENOMIN expertise

  • Personalized genome engineering service to fit our customer needs.
  • Implication in international consortia (near 20 different consortia) to benefit from the last technics and scientific expertise.
  • Continuous R&D activity to improve our technics and success rate and propose our customers the best approach for their projects.

Publications