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  1. Home
  2. Tools & Technologies
  3. Model creation - Personalized genome engineering
  4. Structural variants
Mouse, Rat or Cell?
CRISPR/Cas9 Genome Editing
Homologous Recombination in ES cells
Genotyping
Knock-out
Knock-in
Rosa26 Targeting Overexpression
Humanization
Structural variants
Flex models
Pronuclear Injection
In vivo Viral Transduction
Flp and Cre Deleters
Our recommendations

Structural variations (large deletions, inversions i.e. copy number variations and duplications & translocations) contribute to genome variability and are often associated with diseases.

This technology can be used to generate monosomic and trisomic syndromes in the mouse.

 
 Target DNA
  > > >
 
Inversion
> < >  
 
Z flèche bas grosse
  >   >
Z flèche haut droit grosse  
Z flèche droite grosse
Duplication
> > > >
    >  
Z flèche bas droit grosse  
   
Deletion
> >    

 

Which technic can be used ?

 

For structural variants genration request please contact us

PHENOMIN expertise

  • Personalized genome engineering service to fit our customer needs.
  • Implication in international consortia (near 20 different consortia) to benefit from the last technics and scientific expertise.
  • Continuous R&D activity to improve our technics and success rate and propose our customers the best approach for their projects.

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