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Genetic drift

The impact of health status and genetic quality on phenotype is usually underestimated despite it participates to results reproducibility and reliability.

Genetic drift is the constant tendency of alleles' number to evolve in a population, even in the absence of selective forces.

You can reduce genetic drift's impact by

  • Cryopreserving your model: in case of genetic drift or any other problem that might affect your model, you can recover the original strain and pursue your research with a minimal lost of time and money.
  • Refreshing your colony every 5-10 generations by backcrossing to the inbred strain.
  • Replacing the breeders at most every 2 years. PHENOMIN is importing new breeders from its supplier twice a year.