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Axenic & Gnotoxenic derivation

  • For 20 years PHENOMIN has been proposed mouse axenization through caesarean procedure. This technique allows axenic animals derivation from mice with a conventional health status. Derived mice are free of any detectable microorganisms.
  • Gnotoxenization consists in colonizing axenic animals by one or more known microorganisms. This method allows the provision of mice carrying known and controlled flora.
  • Theses services are carried out within isolators. The axenic or gnotoxenic status are controlled by sanitary services.


  1. PHENOMIN refines its expertise  by developping axenization by embryo transfer in order to reduce the number of animals used. 
  2. PHENOMIN transfers its expertise to adapt it to the rat. Rat axenization and gnotoxenisation will be as soon as possible provided as a service to help you to manage your favorite rat models.