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The international jury convened by the ANR makes a very favourable evaluation of PHENOMIN
On the June 16th, 2019, the PHENOMIN infrastructure defended its activity report for the period 2011-2018 and its proposal for 2020-2024 in front of an international jury convened by the ANR. After 15 minutes of presentation, an in-depth discussion on progress and future developments continued between the 3 PHENOMIN representatives and the panel of experts for 45 minutes. The evaluation of PHENOMIN was sent to us in August 2019 with the following general comment:
“The face-to-face meeting with representatives of the PHENOMIN supported the excellent report/application and the panel can state that PHENOMIN is mature, excellent research infrastructure of great importance to research community of France and with global impact. PHENOMIN has already provided. Representatives of the RI explained also the PHENOMIN’s further development within the CELPHEDIA, where the PHENOMIN should take a lead as a central element, increasing its impact scientific community working with animal models, also other than rodents, thus disseminating their knowledge and expertise over the broad French and international research community.”
The Directors of the PHENOMIN Centres, as well as all the managers of work programmes, would like to thank and congratulate all their colleagues for this evaluation which will commit us to a new period of activity of 5 years to serve the scientific community.
We will all face new challenges and as Centre Directors we are confident that we can meet them together to provide better services and new tools to the scientific community.
Our colleagues at MRC Harwell have worked together with Actual Analytics in order to develop the Home Cage Analysis system (HCA), which provides provides 24/7 monitoring of rodent behaviours in a group-housed environment that is beneficial from both data and welfare perspectives. The challenge was initially proposed by the NC3Rs CRACK IT initiative and finally results to the exciting citizen science project “Rodent Little Brother: Secret Lives of Mice “ . The project was launched in early july, this summer.
People contributes to help scientist to get a computer algorithm to track and annotate mouse behaviour for them, getting involved in a project that has the potential to refine experimental procedures and finally to change the way mice and other animals are studied in the laboratory.
To get informed and involved in the project, visit the Rodent Little Brother Home Page.
The International Mouse Phenotyping Consortium’s (IMPC) 10-year strategy presents a bold ambition for the future functional annotation of the genome and deciphering genetic variation in the context of gene function and disease. 2020 will mark the 10th anniversary of the consortium, and then IMPC presents a strategy that encompasses completion of Phase 2, and execution of Phases 3 and 4. PHENOMIN, which has come with other partners to produce this strategy, is really proud of its involvement to this huge project since its inception as a leader from mouse genetics centres across the world.
The 6 key goals of IMPC for 2021–2030 is to deliver broad-based genomic insights into the function of human genetic variation in both coding and non-coding sequences that underpins future developments in precision medicine, rare disease, clinical genetics, and healthy living. This strategy document includes a statement on the underpinning rationale for how mouse genetics and mouse models inform gene function, human disease, and clinical genetics and a clear description fo each key goals.
FELASA, the Federation of European Laboratory Animal Science Associations, represents over 4000 specialists in the field of laboratory animal science from 28 countries and 21 constituent associations.This triennial congress has grown to become the largest European laboratory animal science event attracting almost 2000 participants. This congress is always organized together with one of the FELASA Constituent Associations, which gives us all a great opportunity to familiarize ourselves with the cultural features of different countries in Europe. This time our host will be CLASA, Czech Laboratory Animal Science Association.
The FELASA Congress is a scientific and educational event, offering the current knowledge on the use and welfare of animals in experiments and how to make improvements in these areas: in Prague, a special issue will be the correct reporting of animal research. Animal welfare, ethical aspects, legislation and education are obvious parts of congress topics. We will also have the newest information and recommendations on how to working with aquatics and some other rarely used species.
FELASA Congress is not only science and education. It is also a large exhibition, showing the recent updates in animal care materials and equipment, animal use and health programs, and research equipment. You will have the opportunity to talk with the representatives from the companies exhibiting, and get information on all new equipment, techniques and almost everything needed when working with laboratory animals.
And finally – professional and social contacts are something invaluable in a face-to-face environment. This is an integral part of the FELASA Congress: meeting colleagues from all over Europe – and beyond – renewing old and making fruitful new acquaintances by means of informal conversations.
The FELASA Congress is the perfect occasion to combine continuing education with informal exchanges of ideas.
A. AYADI, from PHENOMIN-ICS is attending the meeting
INFRAFRONTIER2020 project - Trans-national Access call for proposals (June 2019)
The INFRAFRONTIER mouse clinics offer the examination of mouse mutants using a broad and standardised phenotypic check-up covering key research areas such as behaviour, clinical chemistry, immunology, energy metabolism, and lung function amongst others. If phenotypes are uncovered by the primary assays, mouse mutants can be subjected to more detailed analyses in hypothesis driven and disease focussed phenotyping pipelines.
In this specialised phenotyping call we provide access to a comprehensive panel of phenotyping tests, relying on standardized and customized protocols in key therapeutic areas. There are 2 proposals:
The second one is proposed by PHENOMIN-CIPHE. Please find below the application form :
PATHBIO, Precision Pathobiology for Disease Models, is happy to announce the course will be offered from July 15-26, 2019 in Barcelona. The first course on Mouse Embryology, Anatomy, Histology, and anatomical basis of Imaging will take place in the Veterinary School at the Universitat Autònoma de Barcelona (www.uab.cat). The aim is to provide graduate, master, PhD and postdoc students with basic and expert knowledge to phenotype morphologically mouse models of human diseases.
PHENOMIN-ICS is involved in this nice course programme.
There is no fee for this course. Participants have to organize travel and accommodation themselves and cover the corresponding expenses. Interested participants should apply with CV and letter of motivation to Jesús Ruberte (jesus.ruberte@uab.es). Deadline for applications is May 31st, 2019. Accepted participants will be informed middle of June.
Sign up now for the latest Wiley Webinar: Dr. Hervé Luche, PHENOMIN-CIPHE presents new techniques for more parameters, more informative phenotypes: Systematic phenotyping approaches;
with its cutting-edge expertise in mouse genetics and immunology, PHENOMIN-CIPHE aims to develop and analyze, in a massively parallel and standardized mode, mouse KO/KI models, to understand the function of the mouse immune system under normal and infectious conditions. CIPHE has the unique ability to phenotype all the cellular components of the immune system, under normal conditions or confronted with pathogens by, integrating current cutting-edge research and technical knowledge in cytometry.
The 33rd edition of the annual conference of the International Mammalian Genome Society is held in Strasbourg, France !
We welcome you to the PHENOMIN-ICS and IGBMC ! We are planning an exciting meeting on mammalian genetics and genomics. The perpetual evolution of mammalian genomics is the main focus of IMGS' annual conferences. The meeting will begin with five Workshops followed by a Student Satellite Symposium that offers the opportunity for scientists to compete for awards and presentation slots in the main meeting. Indeed, most of the talks are selected from submitted abstracts and there are poster presentations as well ! The conference will once again include the popular mentoring lunch where those looking for career advice can interact with established scientists.
The window to register is limited -- abstract, registration and IMGS scholarship application deadline is June 16 !
Limited places available, so register early to save your spot !
For more details, please see https://imgc2019.sciencesconf.org/
Then, do not hesitate, and register as soons as possible ! We look forward to welcoming you to Strasbourg and the 33rd International Mammalian Genome Conference!<o:p></o:p>
PATHBIO, Precision Pathobiology for Disease Models, is happy to announce the course will be offered from July 15-26, 2019 in Barcelona. The first course on Mouse Embryology, Anatomy, Histology, and anatomical basis of Imaging will take place in the Veterinary School at the Universitat Autònoma de Barcelona (www.uab.cat). The aim is to provide graduate, master, PhD and postdoc students with basic and expert knowledge to phenotype morphologically mouse models of human diseases.
PHENOMIN-ICS is involved in this nice course programme.
There is no fee for this course. Participants have to organize travel and accommodation themselves and cover the corresponding expenses. Interested participants should apply with CV and letter of motivation to Jesús Ruberte (jesus.ruberte@uab.es). Deadline for applications is May 31st, 2019. Accepted participants will be informed middle of June.
We invite you to be part of the Imaging Mouse Model Workshop !
Wednesday, April 24th 2019, PHENOMIN-iCS and IGBMC organizes a workkshop dedicated to mouse model imaging (Auditorium, IGBMC).The workshop is hosted by Mouse models of human diseases Departement, Nicolas CHARLET BERGUERAND, Gérard GRADWOHL, Yann HERAULT, Philippe KASTNER, Daniel METZGER, Arnaud POTERSZMAN, Bernardo REINA SAN MARTIN
Starting 02:00pm - FREE but mandatory registration
Join us !
CRISPR-Cas9 is a rapid and cost effective technology to generate mouse and rat mutant models, however, its impact on the genome still requires careful consideration. For further insight we are pleased to present the following Charles River-hosted and Labroots-hosted webinars presented by G. Pavlovic and M-C Birling from PHENOMIN-ICS
PHENOMIN-ICS works with you from concept to model creation using homologus recombination, latest CRISPR/Cas9 and RNAi technology, and either other trangenic technics to deliver the most relevant model for your application. The effective research with rodent models depends on finding the best appropriated model for your project. How can we help you? Request a quote or email us.
More information at http://www.phenomin.fr/en-us/contact/
Objectives:
The course is conducted in French- Acces to detailed program and registration procedure
CNRS formation entreprises
PHENOMIN's contact: stephanie.lerondel@cnrs-orleans.fr
More information at https://cnrsformation.cnrs.fr/stage-19193-Imagerie-du-petit-animal--evolution%2C-potentiel%2C-limites.html?mc=imagerie
Objectives
The course is conducted in French- Acces to program and registration
CNRS formation entreprises
PHENOMIN's contact: lopes@cnrs-orleans.fr
More information at https://cnrsformation.cnrs.fr/stage-19192-La-cryoconservation--un-outil-pour-la-sauvegarde-des-lignees-murines.html?mc=cryoconservation
Objectives
Organisation:
More information at https://cnrsformation.cnrs.fr/stage-20234-Mouse-embryology-practical-training-course.html?mc=embryologie