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Our colleagues at MRC Harwell have worked together with Actual Analytics in order to develop the Home Cage Analysis system (HCA), which provides provides 24/7 monitoring of rodent behaviours in a group-housed environment that is beneficial from both data and welfare perspectives. The challenge was initially proposed by the NC3Rs CRACK IT initiative and finally results to the exciting citizen science project “Rodent Little Brother: Secret Lives of Mice “ . The project was launched in early july, this summer.
People contributes to help scientist to get a computer algorithm to track and annotate mouse behaviour for them, getting involved in a project that has the potential to refine experimental procedures and finally to change the way mice and other animals are studied in the laboratory.
To get informed and involved in the project, visit the Rodent Little Brother Home Page.
The International Mouse Phenotyping Consortium’s (IMPC) 10-year strategy presents a bold ambition for the future functional annotation of the genome and deciphering genetic variation in the context of gene function and disease. 2020 will mark the 10th anniversary of the consortium, and then IMPC presents a strategy that encompasses completion of Phase 2, and execution of Phases 3 and 4. PHENOMIN, which has come with other partners to produce this strategy, is really proud of its involvement to this huge project since its inception as a leader from mouse genetics centres across the world.
The 6 key goals of IMPC for 2021–2030 is to deliver broad-based genomic insights into the function of human genetic variation in both coding and non-coding sequences that underpins future developments in precision medicine, rare disease, clinical genetics, and healthy living. This strategy document includes a statement on the underpinning rationale for how mouse genetics and mouse models inform gene function, human disease, and clinical genetics and a clear description fo each key goals.
FELASA, the Federation of European Laboratory Animal Science Associations, represents over 4000 specialists in the field of laboratory animal science from 28 countries and 21 constituent associations.This triennial congress has grown to become the largest European laboratory animal science event attracting almost 2000 participants. This congress is always organized together with one of the FELASA Constituent Associations, which gives us all a great opportunity to familiarize ourselves with the cultural features of different countries in Europe. This time our host will be CLASA, Czech Laboratory Animal Science Association.
The FELASA Congress is a scientific and educational event, offering the current knowledge on the use and welfare of animals in experiments and how to make improvements in these areas: in Prague, a special issue will be the correct reporting of animal research. Animal welfare, ethical aspects, legislation and education are obvious parts of congress topics. We will also have the newest information and recommendations on how to working with aquatics and some other rarely used species.
FELASA Congress is not only science and education. It is also a large exhibition, showing the recent updates in animal care materials and equipment, animal use and health programs, and research equipment. You will have the opportunity to talk with the representatives from the companies exhibiting, and get information on all new equipment, techniques and almost everything needed when working with laboratory animals.
And finally – professional and social contacts are something invaluable in a face-to-face environment. This is an integral part of the FELASA Congress: meeting colleagues from all over Europe – and beyond – renewing old and making fruitful new acquaintances by means of informal conversations.
The FELASA Congress is the perfect occasion to combine continuing education with informal exchanges of ideas.
A. AYADI, from PHENOMIN-ICS is attending the meeting
INFRAFRONTIER2020 project - Trans-national Access call for proposals (June 2019)
The INFRAFRONTIER mouse clinics offer the examination of mouse mutants using a broad and standardised phenotypic check-up covering key research areas such as behaviour, clinical chemistry, immunology, energy metabolism, and lung function amongst others. If phenotypes are uncovered by the primary assays, mouse mutants can be subjected to more detailed analyses in hypothesis driven and disease focussed phenotyping pipelines.
In this specialised phenotyping call we provide access to a comprehensive panel of phenotyping tests, relying on standardized and customized protocols in key therapeutic areas. There are 2 proposals:
The second one is proposed by PHENOMIN-CIPHE. Please find below the application form :
PATHBIO, Precision Pathobiology for Disease Models, is happy to announce the course will be offered from July 15-26, 2019 in Barcelona. The first course on Mouse Embryology, Anatomy, Histology, and anatomical basis of Imaging will take place in the Veterinary School at the Universitat Autònoma de Barcelona (www.uab.cat). The aim is to provide graduate, master, PhD and postdoc students with basic and expert knowledge to phenotype morphologically mouse models of human diseases.
PHENOMIN-ICS is involved in this nice course programme.
There is no fee for this course. Participants have to organize travel and accommodation themselves and cover the corresponding expenses. Interested participants should apply with CV and letter of motivation to Jesús Ruberte (jesus.ruberte@uab.es). Deadline for applications is May 31st, 2019. Accepted participants will be informed middle of June.
Sign up now for the latest Wiley Webinar: Dr. Hervé Luche, PHENOMIN-CIPHE presents new techniques for more parameters, more informative phenotypes: Systematic phenotyping approaches;
with its cutting-edge expertise in mouse genetics and immunology, PHENOMIN-CIPHE aims to develop and analyze, in a massively parallel and standardized mode, mouse KO/KI models, to understand the function of the mouse immune system under normal and infectious conditions. CIPHE has the unique ability to phenotype all the cellular components of the immune system, under normal conditions or confronted with pathogens by, integrating current cutting-edge research and technical knowledge in cytometry.
The 33rd edition of the annual conference of the International Mammalian Genome Society is held in Strasbourg, France !
We welcome you to the PHENOMIN-ICS and IGBMC ! We are planning an exciting meeting on mammalian genetics and genomics. The perpetual evolution of mammalian genomics is the main focus of IMGS' annual conferences. The meeting will begin with five Workshops followed by a Student Satellite Symposium that offers the opportunity for scientists to compete for awards and presentation slots in the main meeting. Indeed, most of the talks are selected from submitted abstracts and there are poster presentations as well ! The conference will once again include the popular mentoring lunch where those looking for career advice can interact with established scientists.
The window to register is limited -- abstract, registration and IMGS scholarship application deadline is June 16 !
Limited places available, so register early to save your spot !
For more details, please see https://imgc2019.sciencesconf.org/
Then, do not hesitate, and register as soons as possible ! We look forward to welcoming you to Strasbourg and the 33rd International Mammalian Genome Conference!<o:p></o:p>
PATHBIO, Precision Pathobiology for Disease Models, is happy to announce the course will be offered from July 15-26, 2019 in Barcelona. The first course on Mouse Embryology, Anatomy, Histology, and anatomical basis of Imaging will take place in the Veterinary School at the Universitat Autònoma de Barcelona (www.uab.cat). The aim is to provide graduate, master, PhD and postdoc students with basic and expert knowledge to phenotype morphologically mouse models of human diseases.
PHENOMIN-ICS is involved in this nice course programme.
There is no fee for this course. Participants have to organize travel and accommodation themselves and cover the corresponding expenses. Interested participants should apply with CV and letter of motivation to Jesús Ruberte (jesus.ruberte@uab.es). Deadline for applications is May 31st, 2019. Accepted participants will be informed middle of June.
We invite you to be part of the Imaging Mouse Model Workshop !
Wednesday, April 24th 2019, PHENOMIN-iCS and IGBMC organizes a workkshop dedicated to mouse model imaging (Auditorium, IGBMC).The workshop is hosted by Mouse models of human diseases Departement, Nicolas CHARLET BERGUERAND, Gérard GRADWOHL, Yann HERAULT, Philippe KASTNER, Daniel METZGER, Arnaud POTERSZMAN, Bernardo REINA SAN MARTIN
Starting 02:00pm - FREE but mandatory registration
Join us !
@LluisMontoliu has just tweeted: "Today the @EU_H2020 Project PATHBIO is launched in Barcelona, led by Jesús Ruberte @UABBarcelona aiming to teach the future mouse pathologists in Europe. Tomorrow the satellite meeting will be open to the public and I will talk about transparency in laboratory animals research".
PHENOMIN-ICS takes part of the project
The main purpose of the International Mammalian Genome Society is to promote and stimulate research in mammalian genetics from sequencing to functional genomics, mutagenesis and mutant analysis, and to represent the concerns of its members in their professional activities. The company's activities have grown with the growing awareness of the important and unique role of rodent species in biomedical research and current genetics.
The perpetual evolution of mammalian genomics is the main focus of IMGS' annual conferences. The 2 organizers of the 33rd edition are Yann HERAULT (deputy director of the IGBMC, director of PHENOMIN-ICS, Strasbourg and Elected member of the IMGS Secretariat) and Xavier MONTAGUTELLI (head of the Mouse Laboratory, Institut Pasteur, Paris)
The window to register is limited !
Abstract, registration, IMGS and University of Starsbourg scholarship's application deadline is June 23 !
Registration discounted for IMGS members.
For details please see https://imgc2019.sciencesconf.org/
Program:
5 Workshops on Ensembl, GeneWeaver, IMPC, Next Gen Sequencing, and Easi-CRISPR will be on Wednesday, September 25th from 9 - noon.
The IMGC always includes many opportunities for trainees to present their work and to talk with more senior scientists. The Trainee Symposium where students and post docs present their work mainly to an audience of their peers will be Wednesday, September 25th from noon to 6 PM. Three or four of these presentations will be chosen to be presented in the main meeting.
The main meeting runs from Thursday through Saturday finishing with an awards banquet on Saturday evening. The conference will once again include the popular mentoring lunch where those looking for career advice can interact with established scientists on Thursday, September 26th.
Invited speakers:
For questions, please contact:
PHENOMIN-ICS and IGBMC: emailimgc2019@igbmc.fr
IMGSociety :millerdr@med.unc.edu
More information at https://imgc2019.sciencesconf.org/
Attend the French congress in animal laboratory sciences
Cette année, le thème qui sera traité est "la provenance et de l’évolution de l’animal de laboratoire.
"Au nom de l’AFSTAL, j’ai donc le plaisir de vous convier au 45e Colloque de notre Association qui se déroulera du 2 au 4 octobre 2019 dans la ville de La Rochelle et dont le titre sera “Origine et devenir de l’animal de laboratoire”. Dans la lignée des éditions précédentes, nous consacrerons la première session du colloque à la présentation des plateformes locales et des équipes scientifiques des régions de Loire-Atlantique et de Poitou-Charentes. Nous consacrerons ensuite l’ensemble des conférences au “suivi des animaux de laboratoire” dans tous ses états...Nous apporterons encore cette année une attention toute particulière aux retours d’expérience...La plus grande exposition commerciale d’Europe sera accessible durant la totalité du colloque afin de favoriser les discussions et les échanges entre les congressistes et les exposants...Pour le Comité d’Organisation, Frédéric Jacquot, Président de l’AFSTAL"
Rencontrez nous !
Venez nombreux !
More information at https://www.colloque-afstal.com//2019/
Do you want to learn more about abilities of CRISPR-based editing, next-gen editing tools, precision in gene editing and using CRISPR for drug discovery ? Do you want to understand more our activities and our service regarding the CRISPR applications, especially Gene Editing Applications in Animal Model Development for Medical Research ? If so do not hesitate to be part of the webinar series.
Marie-Christine Birling, PHENOMIN-ICS, is talking about , OCT 03, 2019 06:00 AM PDT, "Generating rodent model by CRISPR/Cas9 genome editing".
Labroots organizes virtual conference allows participants to attent a global setting with no travel or cost. The event will remain open 6 months from the date of the live event. The webinars will be available for unlimited on-demand viewing. This virtual conference also offers increased reach for the CRISPR community with a high degree of interaction through live-streaming video and chat sessions. Like the 2018 inagural conference, this event will be produced on their robust virtual platform, allowing attendees to watch, learn and connect seamlessly across all desktop or mobile devices.
More information at https://www.labroots.com/virtual-event/crispr-2019
This training aims to provide a general framework to get scientists started using CRISPR-Cas9 for in vivo gene editing in rodents.
Objectives
Acces to program and registration
CNRS formation entreprises
PHENOMIN's contact: bedu@igbmc.fr and birlingm@igbmc.fr (scientific director of the course)
More information at https://cnrsformation.cnrs.fr/stage-19175-In-vivo-CRISPR-Cas9-genome-editing.html?axe=108
Objectives
Acces to detailed program and registration
CNRS formation entreprises
PHENOMIN's contact: bedu@igbmc.fr and olivia@igbmc.fr (scientific director of the course)
More information at https://cnrsformation.cnrs.fr/stage-19359-Mouse-embryology-practical-training-course.html?mc=embryology
Click here to download the attachment.
Objectives :
The course is conducted in French- Information on program and registration process
CNRS Formation
PHENOMIN's contact: bedu@igbmc.fr and philippe.hoest@inserm.fr (scientific director of the course)
More information at http://www.dgdr.cnrs.fr/SST/CNPS/formations/Doc/ANF%20Pilotage_L3A3_programme2019.pdf
CRISPR-Cas9 is a rapid and cost effective technology to generate mouse and rat mutant models, however, its impact on the genome still requires careful consideration. For further insight we are pleased to present the following Charles River-hosted webinars presented by G. Pavlovic, head of the genetic engineering department of PHENOMIN-ICS
For more information, and to watch the webinar replays on demand, please visit the Charles River Website.
PHENOMIN-ICS works with you from concept to model creation using homologus recombination, latest CRISPR/Cas9 and RNAi technology, and either other trangenic technics to deliver the most relevant model for your application. The effective research with rodent models depends on finding the best appropriated model for your project. How can we help you? Request a quote or email us.
More information at https://www.criver.com/resources/webinar-series-transgenic-mouse-and-rat-model-creation
PATHBIO Imaging mouse master class consists of one of the three intensive courses from PATHBIO consortium. The PathBio project brings together an ERASMUS+ Knowledge Alliance consortium from across the globe to cooperate on pooling resources and expertise in order to build the framework for a European post graduate degree in Precision pathobiology for disease models.
The Imaging mouse master class will take place from the 4th to the 8th of November, in Strasbourg (from Monday morning to Friday afternoon).
The detailed program is right now in progress and will be defined as soon as possible- HAVE a look to the previous PATHBIO summer school on Anatomy & Pathology
The registration is not yet open: SAVE THE DATE !
More information at http://pathbio.org/
Objectives:
The course is conducted in French- Acces to detailed program and registration procedure
CNRS formation entreprises
PHENOMIN's contact: stephanie.lerondel@cnrs-orleans.fr
More information at https://cnrsformation.cnrs.fr/stage-19193-Imagerie-du-petit-animal--evolution%2C-potentiel%2C-limites.html?mc=imagerie
Objectives
The course is conducted in French- Acces to program and registration
CNRS formation entreprises
PHENOMIN's contact: lopes@cnrs-orleans.fr
More information at https://cnrsformation.cnrs.fr/stage-19192-La-cryoconservation--un-outil-pour-la-sauvegarde-des-lignees-murines.html?mc=cryoconservation