The aim is to facilitate access for the French research community to the services from the unique national infrastructure and scientific expertise of the PHENOMIN’s partners, and to deliver novel mouse lines that providing important opportunities to advance knowledge gene function in relation to human development and disease.
The calls are opened to French research applicants. The project will be submitted to a review process by an external scientific committee based on the scientific evaluation of their project according to the following criteria:
- The PHENOMIN resources mobilized by the project,
- The potential to distribute the model under consideration,
- The potential publicly availability of the data results,
- The innovative nature of the project,
- The scientific interest of the project.
Request services are done on line through the internet common platform from the PHENOMIN website. Each applicant will be informed of the outcome of the evaluation within the timing that has been defined for each call. For the calls that are non-free of charge, the cost of the project will be given to the selected applicant for placing an official order.
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Current call
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PHENOMIN call
There is no open call for proposal at the moment.
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INFRAFRONTIER2020 project - Trans-national Access - involving PHENOMIN
Precision mammalian model development / rat models - January 2019
This Trans-national Access call of the INFRAFRONTIER2020 project supports a total of 3 precision rat model development projects. A complementary call provides support for 12 customised mouse model development projects.
6th Call: CreERT2
We are glad to announce the new PHENOMIN call dedicated to generation and characterization of CreERT2 cell specific promoter driven deleter mouse lines.
Since 2011, PHENOMIN has generated more than 150 models with conditional potential. In the frame of the International Mouse Phenotyping Consortium (IMPC) more than 5,000 genes are already committed to the IMPC pipeline. Most of these models can be driven in conditional alleles.
We aim to maximize the utility of this resource by offering the scientific community with the possibility to nominate the making of new Cre or CreERT2 lines.
5th Call: IMPC
We are glad to announce the 5th PHENOMIN call for proposals for conditional or constitutive knock-out mouse generation and standard phenotyping.
Since 2011, PHENOMIN has generated more than 150 models. In the frame of the International Mouse Phenotyping Consortium (IMPC) more than 5,000 genes are already committed to the IMPC pipeline.
In the frame of this 5th call, we have added constitutive knock-out models to be generated using CRISPR (clustered regularly interspaced short palindromic repeats) genome editing technology.
4th Call: Fondation Maladies Rares
The "Fondation Maladies Rares" and the National Infrastructure PHENOMIN which includes the Institut Clinique de la Souris (ICS, Illkirch), the Centre for Immunophenomics (CIPHE, Marseille) and the Transgenesis and Archiving of Animal Models (TAAM, Orléans, Villejuif) are pleased to launch their 2nd joint call for the creation and exploration of mouse models for rare diseases.
3rd Call: IMPC
We are glad to announce the 3rd PHENOMIN Expressions of Interest for generation of transgenic mouse lines bearing a single gene knock-out (with conditional potential).
Today, through its partnership with the International Mouse Phenotyping Consortium (IMPC) PHENOMIN has generated nearly 150 models and more than 5.000 genes are already committed to the pipeline of the IMPC.
2nd Call: Fondation Maladies Rares
The "Fondation Maladies Rares" and the National Infrastructure PHENOMIN (ICS, TAAM, CIPHE) are pleased to announce the launch the call for joint research projects: "Murine models and rare diseases".
1st Call: IMPC
Through its partnership in the IMPC, PHENOMIN will, over the next 5 years, produce over 235 transgenic mouse lines bearing a single gene knock-out and analyse them using broad-based, high-throughput phenotyping. These knockout mice, together with the wealth of associated data, will serve as a valuable, freely available, resource for French researchers investigating gene function and human pathophysiology.