Current call

PHENOMIN 7th call for proposal


The French Foundation for rare diseases (Fondation maladies rares) and the French National Infrastructure PHENOMIN are pleased to launch their 3rd joint call for the creation and exploration of mouse models for rare diseases.
The call for projects 'Mouse models and rare diseases' aims to give a significant boost to the development of mouse models, in order to:

  • gain a better understanding of the pathophysiological mechanisms involved in rare diseases whose defective genes have been identified;
  • test and validate therapeutic proofs of concept, at the pre-clinical in vivo level.

Indeed, producing these models meets a key objective in the development of a therapeutic strategy. After their initial in vitro testing, therapeutic proofs of concept must be tested in a living model that recapitulates as closely as possible both the phenotype and biological defects associated to the human disease. Such a model should provide appropriate data regarding the safety and the efficiency of the drug, thus evaluating its benefit/risk ratio, prior to conducting early phases of a therapeutic trial. PHENOMIN and the French Foundation for rare diseases combine their efforts in order to achieve these objectives through the joint call for proposals for the generation and characterization of mouse models, dedicated to rare diseases. This action is part of the objectives of PHENOMIN to develop mouse model resources that will be made available to the scientific community.
 
Upload the call for proposal Icon 2016-MousemodelsRareDiseases-final.pdf (732.9 KB)

Submission deadline for proposals: February 9, 2017, 5:00 pm
 
On line submission: HERE.